4-Hydroxybenzaldehyde → 4-(2-quinolinylmethoxy)Benzaldehyde

HRID 1170294Notes

Reaction equation

C[O:2][C:3](=O)[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][C:12]2[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[N:13]=2)=[CH:6][CH:5]=1.OC1C=CC(C=O)=CC=1>>[N:13]1[C:14]2[C:19](=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:20]=[CH:21][C:12]=1[CH2:11][O:10][C:7]1[CH:8]=[CH:9][C:4]([CH:3]=[O:2])=[CH:5][CH:6]=1

Participants

Reactant 2

HCID 1264-Hydroxybenzaldehyde

HCID 19934817Methyl 4-(2-quinolinylmethoxy)benzoate

Product 1

HCID 145789604-(2-quinolinylmethoxy)Benzaldehyde

Procedure

Following the procedure for the preparation of 4-(Quinolin-2-ylmethoxy)-benzoic acid methyl ester but substituting 4-Hydroxy-benzaldehyde provided the title compound. MS: (M+H m/z=264.2).

Sources & evidence

ORD record: ord-b3decc8d830349baabe0386797e84ffa
Source dataset: uspto-grants-2010_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07825254B2

Reaction notes

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