HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 178464152, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 178464154 | HCID 178464154 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178464152 | HCID 178464152 | 89.9% |
Reaction Steps
Cis-1-diethylamino-3-hydroxycyclobutane hydrochloride (100 mg, 0.557 mmol) was dissolved in methanol (3.0 ml), and thereto was added 1N aqueous sodium hydroxide solution (0.560 mL, 0.560 mmol). The mixture was evaporated, and thereto were added ethyl acetate and tetrahydrofuran, and the mixture was dried over sodium sulfate, and filtered. The filtrate was evaporated to give the titled compound (71.7 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825155B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-ae638c4064f74409b76e79ced386a16a |
| Source note | uspto-grants-2010_11 |