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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1170422Generated: November 1, 2026

Sodium Hydroxide → HCID 178464152, compound

https://huagongshe.com/reaction/1170422

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 178464154HCID 178464154—
SolventMethanolHCID 887—
ProductHCID 178464152HCID 17846415289.9%

Reaction Steps

Cis-1-diethylamino-3-hydroxycyclobutane hydrochloride (100 mg, 0.557 mmol) was dissolved in methanol (3.0 ml), and thereto was added 1N aqueous sodium hydroxide solution (0.560 mL, 0.560 mmol). The mixture was evaporated, and thereto were added ethyl acetate and tetrahydrofuran, and the mixture was dried over sodium sulfate, and filtered. The filtrate was evaporated to give the titled compound (71.7 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825155B2
Source datasetuspto-grants-2010_11
ORD IDord-ae638c4064f74409b76e79ced386a16a
Source noteuspto-grants-2010_11