Piperidine → HCID 58654441, compound

Participants

Reaction Steps

To a solution of 2-[(2-imidazol-1-yl-6-methyl-pyrimidin-4-ylmethyl)-carbamoyl]-pyrrolidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester (435 mg, 0.855 mmol) in dimethylformamide (3.2 mL) was added piperidine (800 μL, 8.09 mmol) at r.t. The solution was stirred for 20 min then concentrated under vacuum to afford 244 mg of pyrrolidine-2-carboxylic acid (2-imidazol-1-yl-6-methyl-pyrimidin-4-ylmethyl)-amide as a brown oil. [M+H]+ 287.28.

Provenance & Evidence