Phenyltrimethylammonium bromide dibromide → HCID 66790690, compound

HRID 1170822Notes

Reaction equation

HRID 1170822 reaction equation
[Br-:1].[Br-].[Br-].C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1.[F:34][CH:35]([F:48])[O:36][CH2:37][CH:38]([CH3:47])[C:39]([C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=1)=[O:40]>O1CCCC1>[Br:1][C:38]([CH3:47])([CH2:37][O:36][CH:35]([F:48])[F:34])[C:39]([C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=1)=[O:40]

Participants

4

Reactant 2

HCID 17977687Phenyltrimethylammonium bromide dibromideHCID 66790383HCID 66790383, compound

Product 1

HCID 66790690HCID 66790690, compoundYield 172.4%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

3.58 g of phenyltrimethylammonium tribromide was added to a mixture comprising 2.04 g of 3-difluoromethoxyisobutyrophenone and 30 ml of tetrahydrofuran, followed by a reaction for two hours at room temperature. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to obtain 2.79 g of oily α-bromo-3-difluoromethoxyisobutyrophenone.

Workup

  1. customfollowed by a reaction for two hours at room temperature
  2. filtrationThe reaction mixture was filtered
  3. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-defc11e4d45b4549a1f909dae5b6bc68
Source dataset
uspto-grants-2010_11
Patent number
US07829501B2

Reaction notes

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