反应详情

To a suspension of compound 5d (0.26 g, 1 mmol) in ethoxyethanol (30 mL) was added NH2OH·HCl (0.20 g, 3 mmol). The reaction mixture was heated with stirring under microwave irradiation (100 W) for 30 min (by TLC monitoring), followed by concentration in vacuo. A solid thus obtained was recrystallized from MeOH to give the title compound 6a (0.20 g, 73% yield).

1. temperatureThe reaction mixture was heated
2. concentrationfollowed by concentration in vacuo
3. customA solid thus obtained
4. customwas recrystallized from MeOH