HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylacetamide → 2-Methyl-4(3H)-quinazolinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylacetamide | HCID 31374 | — |
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Reactant | HCID 68679541 | HCID 68679541 | — |
| Product | 2-Methyl-4(3H)-quinazolinone | HCID 135400457 | — |
Reaction Steps
2-Methylbenzoxazin-4-one (0.24 mole) and ammonium acetate (0.30 mole) is given in 50 ml of N,N-dimethylacetamide and then heated to 160° under a nitrogen blanket for 2 h. After cooling to rt, the white solid is collected by filtration and washed with diethyl ether. Air drying give 2-methyl-quinazolin-4-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07829566B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-80c60db7c08e4cd6a3132bad404d67a3 |
| Source note | uspto-grants-2010_11 |