Hydrochloric Acid → HCID 178478838, compound

Participants

Reaction Steps

The HCl salt of ({[(tert-butoxycarbonyl)amino-(tert-butoxycarbonyl)iminomethyl]aminooxy}ethyl)amine (90.5 mg, 255 μmol) (WO 2004/091613 A2) was treated with 12 M HCl (aq) (210 μL, 2.5 mmol) in one portion at rt, and was then stirred at rt for 20 min. The resulting thick white slurry was concentrated under rotary evaporation at rt, and the residue was taken up in toluene (3×3 mL) with repeated rotary evaporation and high vacuum to yield the title compound as an off-white powder (52.9 mg, quantitative yield).

Provenance & Evidence