2-Methoxyethylamine → HCID 59553066, compound

Participants

Role	Name	HCID	Charge
Reactant	2-Methoxyethylamine	HCID 8018	—
Reactant	3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide	HCID 66737969	—
Product	HCID 59553066	HCID 59553066	—

Reaction Steps

Compound is prepared from 3-fluoro-N-[4-(2-methanesulfonyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-5-piperidin-1-yl-benzamide and 2-methoxyethylamine according to conditions described in general procedure C. Mp: 87-88° C.; 1H NMR (400 MHz, DMSO-d6) δ 1.60-1.63 (m, 6 H), 3.00-3.38 (m, 1 H), 6.20-6.40 (m, 1 H), 6.99 (d, J=12.4 Hz, 1 H), 7.09-7.18 (m, 2 H), 7.40 (d, J=7.7 Hz, 1 H), 7.46 (s, 1 H), 7.55-7.62 (m, 3 H), 7.82 (d, J=8.0 Hz, 1 H), 7.99 (d, J=8.0 Hz, 1 H), 8.23 (s, 1 H), 10.43 (s, 1 H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07829560B2
Source dataset	uspto-grants-2010_11
ORD ID	ord-6b32d509c2e844128c68345bd367f8fd
Source note	uspto-grants-2010_11