1,2,3-Benzothiadiazole-5-carboxylic acid → HCID 59553346, compound

HRID 1171374Notes

Reaction equation

HRID 1171374 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[N:2]1.[N:13]1([CH2:19][CH2:20][O:21][C:22]2[C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[C:25]([NH2:32])=[CH:24][CH:23]=2)[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1>>[N:13]1([CH2:19][CH2:20][O:21][C:22]2[C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[C:25]([NH:32][C:10]([C:8]3[CH:7]=[CH:6][C:5]4[S:1][N:2]=[N:3][C:4]=4[CH:9]=3)=[O:12])=[CH:24][CH:23]=2)[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1

Participants

3

Reactant 2

HCID 27354581,2,3-Benzothiadiazole-5-carboxylic acidHCID 110439124-(2-Morpholinoethoxy)naphthalen-1-amine

Product 1

HCID 59553346HCID 59553346, compound

Procedure

Compound is prepared from benzo[1,2,3]thiadiazole-5-carboxylic acid and 4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-ylamine according to conditions described in general procedure G. Mp: 188-190° C.; 1H NMR (300 MHz, CDCl3) δ 2.70 (t, 4H), 3.00 (t, 2H), 3.78 (t, 4H), 4.30 (t, 2H), 6.82 (d, 1H), 7.58 (m, 2H), 7.65 (d, 1H), 7.88 (d, 1H), 8.15 (d, 1H), 8.25 (d, 2H), 8.40 (s, 1H), 9.18 (s, 1H); MS 435 (M+1).

Sources & evidence

ORD record
ord-b333ae482c6b422a971845289e45f200
Source dataset
uspto-grants-2010_11
Patent number
US07829560B2

Reaction notes

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