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Diisobutylaluminum hydride → (2-(Benzyloxy)-4-iodophenyl)methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diisobutylaluminum hydride | HCID 14487 | — |
| 反応物 | Methyl 2-(benzyloxy)-4-iodobenzoate | HCID 66990993 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | (2-(Benzyloxy)-4-iodophenyl)methanol | HCID 68417547 | — |
反応手順
The procedure is the same as that described above, using 14 g of methyl 2-benzyloxy-4-iodobenzoate, 350 ml of toluene and 72 ml of DiBAlH. The product is purified by chromatography on a silica column, eluted with a heptane/ethyl acetate 9:1 mixture. After evaporation of the solvents, 12.2 g (99%) of the expected compound are recovered in the form of a yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07829588B2 |
| 出典データセット | uspto-grants-2010_11 |
| ORD ID | ord-6be7912f618e4550a1e5a34776ba1fef |
| 出典メモ | uspto-grants-2010_11 |