HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-amino-1H-pyrrole-2-carboxylate → 3-{[2-{[tert-Butyl(dimethyl)silyl]oxy}-2-(4-methoxyphenyl)ethyl]amino}-1H-pyrrole-2-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-amino-1H-pyrrole-2-carboxylate | HCID 2773439 | — |
| Reactant | {[tert-Butyl(dimethyl)silyl]oxy}(4-methoxyphenyl)acetaldehyde | HCID 86623127 | — |
| Product | 3-{[2-{[tert-Butyl(dimethyl)silyl]oxy}-2-(4-methoxyphenyl)ethyl]amino}-1H-pyrrole-2-carboxylic acid ethyl ester | HCID 67068499 | 29% |
Reaction Steps
The title compound (0.13 g, 19%) was prepared in accordance with general method A using 3-amino-1H-pyrrole-2-carboxylic acid ethyl ester (0.16 g, 1.07 mmol) and {[tert-butyl(dimethyl)silyl]oxy}(4-methoxyphenyl)acetaldehyde (0.3 g, 1.07 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07829707B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-8e9c06c4169b41b6b0cfff119605107b |
| Source note | uspto-grants-2010_11 |