反应详情

3,4-Dimethylbenzene-1,2-diamine (0.409 g, 3.0 mmol) and dichloroacetic acid (0.768 g, 6.0 mmol) in 4N HCl (10 mL) were heated at 100° C. for two days. After cooling to r.t. the mixture was filtrated and the mother liquor was extracted with chloroform (4 times). The pH was set to 12 using 2M NaOH and the resulting white precipitate was collected by filtration. The crude product was used in the next step without further purification.

1. filtrationwas filtrated
2. extractionthe mother liquor was extracted with chloroform (4 times)
3. filtrationthe resulting white precipitate was collected by filtration
4. customThe crude product was used in the next step without further purification