Sodium Hydroxide → HCID 57995680, compound

HRID 1171922Notes

Reaction equation

HRID 1171922 reaction equation
Cl[CH:2]([OH:5])[CH2:3][CH3:4].[N+:6]([C:9]1([N+:13]([O-:15])=[O:14])[CH2:12][NH:11][CH2:10]1)([O-:8])=[O:7].[OH-].[Na+]>>[CH2:4]([N:11]1[CH2:12][C:9]([N+:13]([O-:15])=[O:14])([N+:6]([O-:8])=[O:7])[CH2:10]1)[CH:3]1[O:5][CH2:2]1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 86636736HCID 86636736, compound

Product 1

HCID 57995680HCID 57995680, compound

Procedure

In step (2), 1-chloropropanol-3,3-dinitroazetidine of Formula IV prepared in step (1) is cooled, and NaOH aqueous solution is slowly dropped. Thus obtained brown solution is warmed to room temperature and stirred for 3-10 hours. The solution obtained is washed with distilled water and then distilled with diethylether. Thus obtained organic layer is dried on K2CO3. The solvent is removed under lowered pressure and 1-glycidyl-3,3-dinitroazetidine is obtained.

Workup

  1. customThe solution obtained
  2. washis washed with distilled water
  3. distillationdistilled with diethylether
  4. customThus obtained organic layer is dried on K2CO3
  5. customThe solvent is removed

Sources & evidence

ORD record
ord-dc8e83242f8c4837bf01bf22ecd15f9e
Source dataset
uspto-grants-2010_11
Patent number
US07829729B2

Reaction notes

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