反应详情

温度

0 °C

To benzaldehyde (2.17 g, 20.4 mmol) in 20 mL of ether, 1 M (trimethylsilyl)methyl magnesium chloride solution in ether (28.6 mL) was added at 0° C. After two hours of stirring at 0° C., a saturated NH4Cl solution was added and the mixture was extracted with ether (3×). The combined organic extract was dried (Na2SO4), filtered, and concentrated to give the title product (4.12 g).

1. extractionthe mixture was extracted with ether (3×)
2. extractionThe combined organic extract
3. dry with materialwas dried (Na2SO4)
4. filtrationfiltered
5. concentrationconcentrated