HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11589233, compound → HCID 16058859, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11589233 | HCID 11589233 | — |
| Reactant | HCID 15953808 | HCID 15953808 | — |
| Reactant | HCID 58657578 | HCID 58657578 | — |
| Product | HCID 16058859 | HCID 16058859 | — |
Reaction Steps
The title compound was prepared from (S)-tert-butyl 5-amino-6-oxo-6-(4-(pyridin-4-yl)piperazin-1-yl)hexylcarbamate and (R)-3-(7-methyl-1H-indazol-5-yl)-2-(4-(2-oxo-1,2-dihydroquinazolin-3 (4H)-yl)piperidine-1-carboxamido)propanoic acid using the same procedure as described for tert-butyl (S)-5-((R)-3-(7-methyl-1H-indazol-5-yl)-2-(4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamido)propanamido)-6-oxo-6-(4-(pyridin-4-yl)piperazin-1-yl)hexylcarbamate. The title compound was obtained in 66% yield. MS (ESI) 850 (M+H) ; Rf=2.07.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834007B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-86edeecfe65d4b18b818edcd56658bb7 |
| Source note | uspto-grants-2010_11 |