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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 117244Generated: October 27, 2026

Tetrahydrofuran → Tert-butyl 4-(4-chloro-2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)phenyl)-4-hydroxypiperidine-1-carboxylate

https://huagongshe.com/reaction/117244

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Reactant2-(2-Bromo-5-chlorophenyl)-4,4-dimethyl-4,5-dihydrooxazoleHCID 23136914—
ReactantButyllithiumHCID 178418339—
ProductTert-butyl 4-(4-chloro-2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)phenyl)-4-hydroxypiperidine-1-carboxylateHCID 46835566—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-1e05bcab0a8640559362196c08361ea0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)