HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-vinyl-benzonitrile → 2-Ethyl-4-fluorobenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-vinyl-benzonitrile | HCID 59556337 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Ethyl-4-fluorobenzonitrile | HCID 23439276 | 77.1% |
Reaction Steps
800 mg 4-Fluoro-2-vinyl-benzonitrile were dissolved in 5 ml methanol. 80 mg palladium (10% on charcoal) were added and the reaction was stirred under a hydrogen atmosphere for one hour. The catalyst was filtered off trough a pad of celite. The filtrate was evaporated to obtain 625 mg 2-Ethyl-4-fluoro-benzonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834030B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-2b38a61d2c924003b8d6f911058d88ae |
| Source note | uspto-grants-2010_11 |