Phthalimide → N-(3-nitrophenethyl)phthalimide

Participants

Reaction Steps

3-Nitrophenethyl alcohol (15 g) was dissolved in tetrahydrofuran (225 ml). After adding triphenylphosphine (26 g) and phthalimide (13.9 g) thereto, the mixture was ice-cooled and diethylazodicarboxylate (15.5 ml) was added dropwise thereinto. After stirring at room temperature for one hour, the resulting crystals were collected by filtration, washed with diethyl ether and dried, to give N-(3-nitrophenethyl)phthalimide as colorless crystals.

Provenance & Evidence