反应详情

Using N-acetyl-N-(3-ethoxycarbonylaminophenethyl)amine (1.0 g, Production Example 30b), a cyclization reaction was run according to the method described in Heterocycles 31 (2), 341 (1990). After the reaction was completed, the reaction solution was poured into ice and basified with potassium carbonate. Then, the solution was extracted with ethyl acetate, and the extract was washed with brine and dried over anhydrous magnesium sulfate. The solvent was evaporated, to give the title compound as a brown oil.

1. customa cyclization reaction
2. additionthe reaction solution was poured into ice
3. extractionThen, the solution was extracted with ethyl acetate
4. washthe extract was washed with brine
5. dry with materialdried over anhydrous magnesium sulfate
6. customThe solvent was evaporated