Hydrochloric Acid → HCID 14610428, compound

Participants

Reaction Steps

3-(2-t-Butoxycarbonylaminoethyl)-ethoxycarbonylaminobenzene (14.96 g, Production Example 36b) was dissolved in ethanol (15 ml), to which was then added hydrochloric acid (15 ml) under ice-cooling, followed by stirring at room temperature for 20 minutes. Hydrochloric acid (12 ml) and ethanol (15 ml) were added thereto, followed by stirring at room temperature for 20 minutes. Then, hydrochloric acid (20 ml) and ethanol (30 ml) were further added thereto, followed by stirring at room temperature for 30 minutes. After evaporating (subjecting azeotropic distillation together with toluene) the solvent, the title compound (11.99 g) was obtained as pale yellow crystals.

Provenance & Evidence