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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1173396Generated: November 1, 2026

4-Hydroxybenzaldehyde → 4-[(Cyclopropylmethyl)(3-{[4-(hydroxymethyl)phenyl]oxy}propyl)amino]-2-(trifluoromethyl)benzonitrile

https://huagongshe.com/reaction/1173396

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-HydroxybenzaldehydeHCID 126—
Reactant4-[(Cyclopropylmethyl)(3-hydroxypropyl)amino]-2-(trifluoromethyl)benzonitrileHCID 11460719—
Product4-[(Cyclopropylmethyl)(3-{[4-(hydroxymethyl)phenyl]oxy}propyl)amino]-2-(trifluoromethyl)benzonitrileHCID 11611118—

Reaction Steps

Synthesized as described in Example 5B from 4-[(cyclopropylmethyl)(3-hydroxypropyl)amino]-2-(trifluoromethyl)benzonitrile and 4-hydroxybenzaldehyde: MS (APCI) m/z 405 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834063B2
Source datasetuspto-grants-2010_11
ORD IDord-f4b566d2d3bd4c3dad41b545759e814f
Source noteuspto-grants-2010_11