HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Bromopropoxy)(tert-butyl)dimethylsilane → 4-[(3-Hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Bromopropoxy)(tert-butyl)dimethylsilane | HCID 607486 | — |
| Reactant | 4-((2,2,2-Trifluoroethyl)amino)-2-(trifluoromethyl)benzonitrile | HCID 43138537 | — |
| Product | 4-[(3-Hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile | HCID 86606248 | — |
Reaction Steps
Synthesized as described in Example 1B from 4-(2,2,2-trifluoro-ethylamino)-2-trifluoromethyl-benzonitrile and [(3-bromopropyl)oxy](1,1-dimethylethyl)dimethylsilane: MS (APCI) m/z 327 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834063B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-df99e4762e194b1a9d2b1c7e0ec97d28 |
| Source note | uspto-grants-2010_11 |