HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetaminophen → N-[4-({3-[[4-Cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]propyl}oxy)phenyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetaminophen | HCID 1983 | — |
| Reactant | 4-[(3-Hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile | HCID 86606248 | — |
| Product | N-[4-({3-[[4-Cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]propyl}oxy)phenyl]acetamide | HCID 11712279 | — |
Reaction Steps
Synthesized as described in Example 1C from 4-[(3-hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and 4-acetamidophenol: MS (APCI) m/z 460 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834063B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-4c730d773c1b4d83a55ab081b5799189 |
| Source note | uspto-grants-2010_11 |