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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1173421Generated: October 29, 2026

4-(Methylsulfonyl)phenol → HCID 11511035, compound

https://huagongshe.com/reaction/1173421

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Methylsulfonyl)phenolHCID 123350—
Reactant4-[(2-Hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrileHCID 86623731—
ProductHCID 11511035HCID 11511035—

Reaction Steps

Synthesized as described in Example 1C from 4-[(2-hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and 4-methanesulfonylphenol: 1H NMR (300 MHz, CDCl3) δ 7.67 (app. d, J=8.8 Hz, 2H), 7.67 (d, J=8.6 Hz, 1H), 7.19 (d, J=2.5 Hz, 1H), 7.05-6.95 (m, 3H), 4.29 (t, J=5.3 Hz, 2H), 4.20 (q, J=8.6 Hz, 2H), 4.05 (t, J=5.1 Hz, 2H), 3.01 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834063B2
Source datasetuspto-grants-2010_11
ORD IDord-00a3baace8994ae6b67652991329ddbe
Source noteuspto-grants-2010_11