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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1173455Generated: October 31, 2026

Acetaminophen → N-[4-({3-[[4-Cyano-3-(trifluoromethyl)phenyl](2,2-dimethylpropyl)amino]propyl}oxy)phenyl]acetamide

https://huagongshe.com/reaction/1173455

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetaminophenHCID 1983—
Reactant4-[(2,2-Dimethylpropyl)(3-hydroxypropyl)amino]-2-(trifluoromethyl)benzonitrileHCID 11347554—
ProductN-[4-({3-[[4-Cyano-3-(trifluoromethyl)phenyl](2,2-dimethylpropyl)amino]propyl}oxy)phenyl]acetamideHCID 11525160—

Reaction Steps

Synthesized as described in Example 1C from 4-[(2,2-dimethylpropyl)(3-hydroxypropyl)amino]-2-(trifluoromethyl)benzonitrile and 4-acetamidophenol: MS (ESI) m/z 448 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834063B2
Source datasetuspto-grants-2010_11
ORD IDord-916d6ad87b18423fb80ce87d77e87b73
Source noteuspto-grants-2010_11