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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1173456Generated: November 1, 2026

4-tert-Butylphenol → 4-[(3-{[4-(1,1-Dimethylethyl)phenyl]oxy}propyl)(2,2-dimethylpropyl)amino]-2-(trifluoromethyl)benzonitrile

https://huagongshe.com/reaction/1173456

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-tert-ButylphenolHCID 7393—
Reactant4-[(2,2-Dimethylpropyl)(3-hydroxypropyl)amino]-2-(trifluoromethyl)benzonitrileHCID 11347554—
Product4-[(3-{[4-(1,1-Dimethylethyl)phenyl]oxy}propyl)(2,2-dimethylpropyl)amino]-2-(trifluoromethyl)benzonitrileHCID 11711995—

Reaction Steps

Synthesized as described in Example 1C from 4-[(2,2-dimethylpropyl)(3-hydroxypropyl)amino]-2-(trifluoromethyl)benzonitrile and 4-tert-butylphenol: MS (ESI) m/z 447 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834063B2
Source datasetuspto-grants-2010_11
ORD IDord-3a79af01566a40c0817ffa334b860acb
Source noteuspto-grants-2010_11