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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1173457Generated: November 1, 2026

4-Fluorophenol → 4-((2,2-Dimethylpropyl){3-[(4-fluorophenyl)oxy]propyl}amino)-2-(trifluoromethyl)benzonitrile

https://huagongshe.com/reaction/1173457

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorophenolHCID 9732—
Reactant4-[(2,2-Dimethylpropyl)(3-hydroxypropyl)amino]-2-(trifluoromethyl)benzonitrileHCID 11347554—
Product4-((2,2-Dimethylpropyl){3-[(4-fluorophenyl)oxy]propyl}amino)-2-(trifluoromethyl)benzonitrileHCID 11596655—

Reaction Steps

Synthesized as described in Example 1C from 4-[(2,2-dimethylpropyl)(3-hydroxypropyl)amino]-2-(trifluoromethyl)benzonitrile and 4-fluorophenol: MS (ESI) m/z 409 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07834063B2
Source datasetuspto-grants-2010_11
ORD IDord-a7f88b88ea44428d8bcf8fc173a3f978
Source noteuspto-grants-2010_11