4'-Bromoacetanilide → N-(4-(3-[[4-Cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]propyl}phenyl)acetamide

HRID 1173483Notes

Reaction equation

HRID 1173483 reaction equation
[CH2:1]([N:4]([CH2:17][C:18]([F:21])([F:20])[F:19])[C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[C:7]([C:13]([F:16])([F:15])[F:14])[CH:6]=1)[CH:2]=[CH2:3].[CH3:22][C:23]([NH:25][C:26]1[CH:31]=[CH:30][C:29](Br)=[CH:28][CH:27]=1)=[O:24]>>[C:9]([C:8]1[CH:11]=[CH:12][C:5]([N:4]([CH2:17][C:18]([F:19])([F:20])[F:21])[CH2:1][CH2:2][CH2:3][C:29]2[CH:30]=[CH:31][C:26]([NH:25][C:23](=[O:24])[CH3:22])=[CH:27][CH:28]=2)=[CH:6][C:7]=1[C:13]([F:14])([F:15])[F:16])#[N:10]

Participants

3

Reactant 2

HCID 76834'-BromoacetanilideHCID 862395134-[2-Propen-1-yl(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

Product 1

HCID 11546736N-(4-(3-[[4-Cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]propyl}phenyl)acetamide

Procedure

Synthesized according to Example 84B from 4-[2-propen-1-yl(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and 4-bromoacetanilide: MS (APCI) m/z 444 (M+1).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-5d86ebde3a234c1eab63e588dc92906a
Source dataset
uspto-grants-2010_11
Patent number
US07834063B2

Reaction notes

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