Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 86639464 | HCID 86639464 | — |
| Solvent | tert-Butyl methyl ether | HCID 15413 | — |
| Product | HCID 13634376 | HCID 13634376 | 104% |
Reaction Steps
Methyl (2R,3R)-2-chloro-3-hydroxyhexanoate (0.9 g, 5 mmol), ethanol (10 ml) and potassium carbonate (2.1 g, 15 mmol) were mixed, and the mixture was stirred at 15° C. for 14 hours. Methyl tert-butyl ether (20 ml) was added. The mixture was washed with water (10 ml) three times. The organic layer was concentrated under reduced pressure to obtain the title compound (0.75 g, yield: 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07834190B2 |
|---|
| Source dataset | uspto-grants-2010_11 |
|---|
| ORD ID | ord-e2528be4d63c4a6f950cd948d0ebfbd5 |
|---|
| Source note | uspto-grants-2010_11 |
|---|
