Hydrochloric Acid → HCID 86639465, compound

HRID 1173769Notes

Reaction equation

HRID 1173769 reaction equation
CC1[O:3][C@H:4]([C:10]([O:12]C)=[O:11])[C@H:5]([CH2:7][CH2:8][CH3:9])[N:6]=1.[ClH:14]>>[ClH:14].[NH2:6][C@@H:5]([CH2:7][CH2:8][CH3:9])[C@H:4]([OH:3])[C:10]([OH:12])=[O:11]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 59203392HCID 59203392, compound

Product 1

HCID 86639465HCID 86639465, compoundYield 90%

Conditions

Temperature
100 °C

Procedure

Methyl (4S,5S)-2-methyl-4-propyl-4,5-dihydro-1,3-oxazole-5-carboxylate (0.68 g, 3 mmol) and 6 N hydrochloric acid (10 ml) were mixed, and the mixture was stirred at 100° C. for 14 hours. The solvent was evaporated away under reduced pressure to obtain the title compound as a white solid (0.50 g, yield: 90%)

Workup

  1. customThe solvent was evaporated away under reduced pressure

Sources & evidence

ORD record
ord-5577f44d2f004d4a8f77e9bab1de2e06
Source dataset
uspto-grants-2010_11
Patent number
US07834190B2

Reaction notes

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