Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86726176 | HCID 86726176 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67420738 | HCID 67420738 | — |
Reaction Steps
A solution containing the product from Example 11E (0.27 g, 0.4 mmol) in THF (4 mL) was treated with an HCl solution (0.70 mL, 4 N in dioxane), heated at 60° C. for 3 hours, cooled to 25° C., and concentrated to give the title compound as the hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07834043B2 |
|---|
| Source dataset | uspto-grants-2010_11 |
|---|
| ORD ID | ord-1989c68c3a5643f09b0197c534987df8 |
|---|
| Source note | uspto-grants-2010_11 |
|---|
