反应详情

温度

50 °C

A solution containing the product from Example 36B (6.8 g, 20.9 mmol) in methanol (30 mL) was treated with triethylamine (5.6 mL, 40.2 mmol), stirred at 50° C. for 2 hours, and concentrated. The residue was chromatographed on silica gel eluting with 0-30% ethyl acetate/dichloromethane to give the title compound (2.53 g, 47% yield).

1. concentrationconcentrated
2. customThe residue was chromatographed on silica gel eluting with 0-30% ethyl acetate/dichloromethane