HRID1174342

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CC(C)(C)OC(=O)N[C@@H](Cc1ccc(-c2ccccn2)cc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

HCID86726240

未命名化合物

PRODUCTS

生成物

结构：N[C@@H](Cc1ccc(-c2ccccn2)cc1)C[C@H](O)[C@@H](N)Cc1ccccc1

HCID67406716

未命名化合物

收率 99.8%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

CONDITIONS

反应条件

温度: 25 °C

PROCEDURE

实验过程

A solution containing the product from Example 133A (0.60 g, 1.07 mmol) in dichloromethane (10 mL) was treated with trifluoroacetic acid (10 mL), stirred at 25° C. for 1 hour, concentrated and partitioned between chloroform and saturated NaHCO3. The organic was dried over Na2SO4, filtered and concentrated to give the title compound (0.386 g, 98% yield).

WORKUP

后处理

concentrationconcentrated
custompartitioned between chloroform and saturated NaHCO3
dry with materialThe organic was dried over Na2SO4
filtrationfiltered
concentrationconcentrated