HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl 3-methyl-N-(methylsulfonyl)-L-valinate → 3-methyl-N-(methylsulfonyl)-L-valine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl 3-methyl-N-(methylsulfonyl)-L-valinate | HCID 86599586 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3-methyl-N-(methylsulfonyl)-L-valine | HCID 61142133 | 106.4% |
Reaction Steps
A solution of Example 152A (59 mg, 0.22 mmol) in 4N HCl in dioxane (1 mL) at 25° C. for 4 h, and the solvents were evaporated to give the crude title compound (49 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07834043B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-b2894561c7914198ba750d8652d40cbb |
| Source note | uspto-grants-2010_11 |