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温度

0 °C

Trifluoroacetic acid (2.4 g) was added dropwise to a solution of benzyl-methoxymethyltrimethylsilanylmethylamine (5.1 g) and 1-methylpyrrole-2,5-dione (2.98 g) in dichloromethane (50 ml) at 0° C. Stirring at 0° C. for 15 minutes was followed by further stirring at room temperature for one hour. The reaction mixture was diluted with dichloromethane, washed with sodium bicarbonate solution and water, dried over magnesium sulfate and concentrated. The product with the molecular weight of 244.30 (C14H16N2O2); MS (ESI): 245 (M+H+) was obtained in this way.

1. stirringby further stirring at room temperature for one hour
2. washwashed with sodium bicarbonate solution and water
3. dry with materialdried over magnesium sulfate
4. concentrationconcentrated
5. customMS (ESI): 245 (M+H+) was obtained in this way