Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1175014Generated: October 30, 2026

4-(4-Chlorophenyl)Imidazole → 4-[5-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-dimethyl-2H-chromene-6-carbonitrile

https://huagongshe.com/reaction/1175014

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Chlorophenyl)ImidazoleHCID 448632—
Reactant2,2-Dimethyl-3,4-epoxy-6-cyanochromanHCID 10867360—
Product4-[5-(4-Chloro-phenyl)-imidazol-1-yl]-2,2-dimethyl-2H-chromene-6-carbonitrileHCID 16048739—

Reaction Steps

Following the procedure in Example 1, using (±)-2,2-dimethyl-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene-6-carbonitrile and 5-(4-chloro-phenyl)-1H-imidazole as starting materials, the title compounds were prepared as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07838553B2
Source datasetuspto-grants-2010_11
ORD IDord-69f4dc1fc1f84ab499178d25b0bb7301
Source noteuspto-grants-2010_11