HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59558650, compound → tert-Butyl 7,9-dioxo-2,6-diazaspiro[3.5]nonane-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59558650 | HCID 59558650 | — |
| Solvent | Acetonitrile--water (1/1) | HCID 18373917 | — |
| Product | tert-Butyl 7,9-dioxo-2,6-diazaspiro[3.5]nonane-2-carboxylate | HCID 57415907 | — |
Reaction Steps
7,9-Dioxo-2,6-diaza-spiro[3.5]nonane-2,8-dicarboxylic acid 2-tert-butyl ester 8-methyl ester (Example 156g)(8.3 g; 26.6 mmol) is dissolved in acetonitrile/water (170 ml; 9/1) and refluxed for 1 hour. The reaction mixture is evaporated to dryness and delivers the title compound as white crystals (6.35 g; 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07838674B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-0b85973da25747c8bc0e765af33525bc |
| Source note | uspto-grants-2010_11 |