HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → HCID 59558387, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 59558610 | HCID 59558610 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 59558387 | HCID 59558387 | — |
Reaction Steps
2-(3-Chloro-4-morpholin-4-yl-phenyl)-8-ethoxy-5,6-dihydro-quinazoline (0.38 g, 1.0 mmol) is refluxed in 20 ml 25% aqueous acetic acid for 1 hour. The reaction mixture is neutralized using solid NaHCO3 and the product is extracted with ethyl acetate. MS (m/z, ES+): 344 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07838674B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-4d4496dd84ff42f6bfcaa410d51ee928 |
| Source note | uspto-grants-2010_11 |