反应详情

温度

100 °C

To a solution of 1-ethanesulfonylpiperazine (1.0 g) in dioxane (10 ml) was added sulfamide (0.51 g). The reaction was then heated at 100° C. for 24 h. The reaction was allowed to cool before being concentrated in vacuo. The residue was stirred in Et2O for 4 h and the mixture filtered to give the product as a white solid. Yield: 1.3 g.

1. temperatureto cool
2. concentrationbefore being concentrated in vacuo
3. filtrationthe mixture filtered