反应详情

A solution of 1-methyl-5-nitroisoquinoline in ethanol was hydrogenated in the presence of 10% palladium carbon at 60 psi for 4 hours. Reaction mixture was filtered through celite bed. Filtrate was concentrated under vacuum to afford the desired compound as pale white solid.

1. customReaction mixture
2. filtrationwas filtered through celite bed
3. concentrationFiltrate was concentrated under vacuum