HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-methyl-5-nitroIsoquinoline → 1-Methylisoquinolin-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-methyl-5-nitroIsoquinoline | HCID 12647950 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Methylisoquinolin-5-amine | HCID 9989490 | — |
Reaction Steps
A solution of 1-methyl-5-nitroisoquinoline in ethanol was hydrogenated in the presence of 10% palladium carbon at 60 psi for 4 hours. Reaction mixture was filtered through celite bed. Filtrate was concentrated under vacuum to afford the desired compound as pale white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842703B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-fac70d2e79b64374ba940d6ce0e8761d |
| Source note | uspto-grants-2010_11 |