HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 135599896, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 135599995 | HCID 135599995 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 135599896 | HCID 135599896 | — |
Reaction Steps
A mixture of methyl 4-{[3-amino-7-methoxy-2-(2-methylphenyl)-4-oxo-4,5-dihydro-2H-pyrazolo[4,3-c]quinolin-9-yl]oxy}butanoate (60 mg) and 2N solution of ammonia in methanol was stirred at room temperature for 5 hours. The reaction mixture was concentrated under reduced pressure, and the residue was purified with column chromatography to obtain the target compound (37 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842701B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-65e7bef094d64c478a84671caffb4fd9 |
| Source note | uspto-grants-2010_11 |