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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1175826Generated: November 2, 2026

Ammonia → HCID 135599896, compound

https://huagongshe.com/reaction/1175826

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 135599995HCID 135599995—
SolventMethanolHCID 887—
ProductHCID 135599896HCID 135599896—

Reaction Steps

A mixture of methyl 4-{[3-amino-7-methoxy-2-(2-methylphenyl)-4-oxo-4,5-dihydro-2H-pyrazolo[4,3-c]quinolin-9-yl]oxy}butanoate (60 mg) and 2N solution of ammonia in methanol was stirred at room temperature for 5 hours. The reaction mixture was concentrated under reduced pressure, and the residue was purified with column chromatography to obtain the target compound (37 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842701B2
Source datasetuspto-grants-2010_11
ORD IDord-65e7bef094d64c478a84671caffb4fd9
Source noteuspto-grants-2010_11