Trimethylsilylacetylene → HCID 68421800, compound

HRID 117586Notes

Reaction equation

HRID 117586 reaction equation
[Br:32][c:33]1[cH:34][cH:35][c:36]([O:37][CH3:38])[c:41]([C:39](=[O:40])[c:42]2[cH:43][cH:44][c:45]([NH:46][c:47]3[cH:48][cH:49][c:50]([F:51])[cH:52][c:53]3[F:54])[cH:55][c:56]2[Cl:57])[cH:58]1.[C:59]([Si:60]([CH3:61])([CH3:62])[CH3:63])#[CH:64].[Cl:1][c:2]1[c:3]([C:17](=[O:18])[c:19]2[c:20]([CH3:31])[cH:21][cH:22][c:23]([C:25]#[C:26][Si:27]([CH3:28])([CH3:29])[CH3:30])[cH:24]2)[cH:4][cH:5][c:6]([NH:8][c:9]2[c:10]([F:16])[cH:11][c:12]([F:15])[cH:13][cH:14]2)[cH:7]1>>[Cl:1][c:2]1[c:3]([C:17](=[O:18])[c:19]2[c:20]([O:40][CH3:39])[cH:21][cH:22][c:23]([C:25]#[C:26][Si:27]([CH3:28])([CH3:29])[CH3:30])[cH:24]2)[cH:4][cH:5][c:6]([NH:8][c:9]2[c:10]([F:16])[cH:11][c:12]([F:15])[cH:13][cH:14]2)[cH:7]1

Participants

4

Reactant 3

HCID 66111TrimethylsilylacetyleneHCID 67314552HCID 67314552, compoundHCID 68417297(5-Bromo-2-methoxy-phenyl)-[2-chloro-4-(2,4-difluoro-phenylamino)-phenyl]-methanone

Product 1

HCID 68421800HCID 68421800, compound

Sources & evidence

ORD record
ord-f1c5763915c74e84b0624ddbf21c62a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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