HRID117586

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66111

Trimethylsilylacetylene

C5H10Si

结构：Cc1ccc(C#C[Si](C)(C)C)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1Cl

HCID67314552

未命名化合物

结构：COc1ccc(Br)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1Cl

HCID68417297

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C#C[Si](C)(C)C)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1Cl

HCID68421800

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f1c5763915c74e84b0624ddbf21c62a3
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (2/10)

反应 SMILES

[Br:32][c:33]1[cH:34][cH:35][c:36]([O:37][CH3:38])[c:41]([C:39](=[O:40])[c:42]2[cH:43][cH:44][c:45]([NH:46][c:47]3[cH:48][cH:49][c:50]([F:51])[cH:52][c:53]3[F:54])[cH:55][c:56]2[Cl:57])[cH:58]1.[C:59]([Si:60]([CH3:61])([CH3:62])[CH3:63])#[CH:64].[Cl:1][c:2]1[c:3]([C:17](=[O:18])[c:19]2[c:20]([CH3:31])[cH:21][cH:22][c:23]([C:25]#[C:26][Si:27]([CH3:28])([CH3:29])[CH3:30])[cH:24]2)[cH:4][cH:5][c:6]([NH:8][c:9]2[c:10]([F:16])[cH:11][c:12]([F:15])[cH:13][cH:14]2)[cH:7]1>>[Cl:1][c:2]1[c:3]([C:17](=[O:18])[c:19]2[c:20]([O:40][CH3:39])[cH:21][cH:22][c:23]([C:25]#[C:26][Si:27]([CH3:28])([CH3:29])[CH3:30])[cH:24]2)[cH:4][cH:5][c:6]([NH:8][c:9]2[c:10]([F:16])[cH:11][c:12]([F:15])[cH:13][cH:14]2)[cH:7]1