反应详情

To a solution of 4,6-dichloro-5-nitro-pyrimidine (100 mg, 0.52 mmol) in anhydrous THF (2 mL) was added aminopyrazole (76 mg, 0.62 mmol). The solution was stirred at RT for 2 hrs and was filtered via short silica gel column. The filtrate that contained product and the unreacted starting pyrimidine was concentrated under vacuum. The resulting residue was used directly without further purification.

1. filtrationwas filtered via short silica gel column
2. concentrationwas concentrated under vacuum
3. customThe resulting residue was used directly without further purification