HuagongsheHuagongshe Chemistry Print Report · For research reference only
1(2H)-Phthalazinone → 1-Chlorophthalazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1(2H)-Phthalazinone | HCID 8394 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Product | 1-Chlorophthalazine | HCID 160793 | — |
Reaction Steps
Compounds of this invention with Formulae I-VIII also could be prepared as illustrated by the exemplary reaction in Scheme 6. Reaction of phthalazin-1(2H)-one with phosphorus oxychloride produced 1-chlorophthalazine, which was reacted with a substituted aniline, such as N-methyl-4-methoxy-aniline, to produce the substituted 1-anilino-phthalazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842805B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-f4bb1095f40e41158e6b753bd289bf94 |
| Source note | uspto-grants-2010_11 |