Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176256Generated: November 1, 2026

HCID 68497857, compound → HCID 68499319, compound

https://huagongshe.com/reaction/1176256

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68497857HCID 68497857—
ReactantBenzyl 3-hydroxy-4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}piperidine-1-carboxylateHCID 68499596—
ProductHCID 68499319HCID 68499319—

Reaction Steps

Analogously to Method D, 3.25 g of benzyl 3-hydroxy-4-{4-[3-(2-methoxybenzyloxy)propoxy]-phenyl}piperidine-1-carboxylate (Example 10f) and 4.05 g of methyl 4-bromomethyl-2-(3-methoxypropoxy)benzoate are reacted. The title compound is obtained as a slightly yellowish oil. Rf=0.30 (1:2 toluene-EtOAc); Rt=6.00.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842688B2
Source datasetuspto-grants-2010_11
ORD IDord-d27a559b9cf04ba69c7e8ab274c35e55
Source noteuspto-grants-2010_11