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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176347Generated: October 27, 2026

2-(3-Bromopropoxy)-1-methoxy-3-methylbenzene → HCID 68503836, compound

https://huagongshe.com/reaction/1176347

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Bromopropoxy)-1-methoxy-3-methylbenzeneHCID 53846604—
ReactantTert-butyl 4-(4-hydroxyphenyl)-3-[1-(3-methoxypropyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-ylmethoxy]piperidine-1-carboxylateHCID 68501561—
ProductHCID 68503836HCID 68503836—

Reaction Steps

Analogously to Method I, 0.100 g of tert-butyl 4-(4-hydroxyphenyl)-3-[1-(3-methoxypropyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-ylmethoxy]piperidine-1-carboxylate (Example 44d) and 0.065 g of 2-(3-bromopropoxy)-1-methoxy-3-methylbenzene are used to prepare the title compound. Rf=0.26 (2:1 EtOAc-heptane); Rt=6.05.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842688B2
Source datasetuspto-grants-2010_11
ORD IDord-9391f2d6d4ce450abe297cfc666af6dd
Source noteuspto-grants-2010_11