HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorobenzimidazole → HCID 11660993, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorobenzimidazole | HCID 78572 | — |
| Reactant | 3,4-Difluorobenzylamine | HCID 123572 | — |
| Reactant | 4-(Bromomethyl)-1,2-difluorobenzene | HCID 581436 | — |
| Product | HCID 11660993 | HCID 11660993 | — |
Reaction Steps
The title compound was prepared by Procedure B in two steps from 2-chloro-benzimidazole, 3,4-difluorobenzyl bromide and 3,4-difluorobenzylamine. The product was isolated by column chromatography to give the title compound as the free base (oil). MS(ES+) m/z 386 ([M+1]+, 100). 1NMR (DMSO-d6) δ 4.59 (d, 2H), 5.30 (s, 2H), 6.87-6.97 (m, 3H), 7.16-7.49 (m, 8H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842817B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-6753df362b8843f4863d8bc875ab12d0 |
| Source note | uspto-grants-2010_11 |