Ethylamine → N-ethyl-2-nitrobenzenesulfonamide

HRID 1176718Notes

Reaction equation

HRID 1176718 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10](Cl)(=[O:12])=[O:11])([O-:3])=[O:2].[CH2:14]([NH2:16])[CH3:15]>O>[CH2:14]([NH:16][S:10]([C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[N+:1]([O-:3])=[O:2])(=[O:12])=[O:11])[CH3:15]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 155402-Nitrobenzenesulfonyl chloride

Product 1

HCID 744706N-ethyl-2-nitrobenzenesulfonamide

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

2-nitrobenzenesulfonyl chloride (10 g) is added portion-wise to 70% ethylamine in water at 0-5° C., maintaining the temperature. It is stirred for 15 minutes until completing the transformation. Water (80 mL) is added, maintaining the temperature. It is stirred for 30 minutes. It is filtered, washed and dried, obtaining 8.97 g of N-ethyl-2-nitrobenzenesulfonamide.

Workup

  1. temperaturemaintaining the temperature
  2. temperaturemaintaining the temperature
  3. stirringIt is stirred for 30 minutes
  4. filtrationIt is filtered
  5. washwashed
  6. customdried

Sources & evidence

ORD record
ord-19a61b390a364cd58f8acbef0d875aa7
Source dataset
uspto-grants-2010_11
Patent number
US07842821B2

Reaction notes

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