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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176799Generated: October 25, 2026

Eosin → 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid

https://huagongshe.com/reaction/1176799

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEosinHCID 11048—
ReactantDisodiumHCID 141233—
ReactantEosin_YHCID 20685766—
SolventWaterHCID 962—
Product2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acidHCID 3383—

Reaction Steps

With total consumption of the fluorescein, the bromination reaction leads to the formation of a single product, tetrabromofluorescein (4Br—F), the disodium salt of which is commercially known as Eosin Y. The final reaction mixture is diluted in water and the product is extracted from the mixture with ethyl acetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842826B2
Source datasetuspto-grants-2010_11
ORD IDord-056a597e74014b6f9e496c2103f8b8aa
Source noteuspto-grants-2010_11